Anyone who’s familiar with cannabis or has consumed cannabis in the past, you’ve probably also heard about the entourage effect. This effect refers to the interaction that takes place between cannabinoids such as CBN, CBD, THC, CBG, terpenes, and other 100+ cannabinoids to provide maximum health benefits. This phenomenon is also referred to as the whole plant effect and it emphasizes the fact that a whole plant can provide better results than isolated cannabinoids.
These days everyone in the cannabis industry talks about the entourage effect. The term is used so much so that cannabis companies do not shy away from marketing the entourage effect vehemently. However, what is the essence of the entourage effect? Are we familiar with the different nuances of the effect? How should we understand the entourage effect in the light of emerging studies? All these questions require intensive research and in-depth analysis. We have a few studies that dug deeper into the concept of the entourage effect and its phenomenon, with some studies questioning the efficacy of this effect. So, what do we really know about the entourage effect? Read on to find out.
Understanding the Entourage Effect
First and foremost, we have studies and pieces of evidence that show one cannabinoid can boost the effect of other cannabinoids. For instance, little amounts of THC can enhance the performance of CBD, terpenes, and other cannabinoids. When in tandem with each other these cannabinoids provide maximum benefits. That said, now lets us take a look at a study on breast cancer tissue and how the presence of cannabinoids improved the results. The only exception, in this case, is that the study was conducted in vitro and tested on animals as well.
The study revealed that cannabis extracts helped reduce the growth of cancer cells more effectively than isolated extracts of THC. The author of the study also went on to say that presence of cannabigerol along with THCA (tetrahydrocannabinolic acid) accounted for increased benefits. In contrast, isolated extracts of THC were not effective.
In addition to this, there was another study that compared the effects of the whole plant extract to isolated extracts. This study, however, concluded that whole plant extracts were just as effective in the treatment of epilepsy, but with 25% less amount.
Does This Mean the Entourage Effect Is Real?
Some cannabis experts and scientists believe that the entourage effect is real. The only problem is that we do not have enough research to show how the interactions work in the case of the entourage effect. While the data or research that we have accounted for effective treatment in the case of a few medical conditions, other conditions can be treated effectively with CBD and THC isolates. So, this means that even if you get 420 evaluations in Oakland for the treatment of a specific condition, there isn’t enough data to show whether whole-plant extracts work better or isolates.
In order to be sure, while getting a medical marijuana card in Oakland, CA talk to a cannabis doctor, and learn which products work effectively in the case of your medical condition. Also, this doesn’t mean that theory related to the entourage is bizarre and unreal. Of course, we also have studies digging deep into the understanding of the entourage effect. The only problem is that we still do not have enough proof. All thanks to the federal status of cannabis legalization. You see, cannabis is still illegal on the federal level. And as long as it remains illegal scientists and doctors are bound to stay away from cannabis research. Although there are centers and institutions assigned for cannabis research, yet the research conducted in these institutions is limited. That’s why we still do not have enough evidence associated with cannabis and its cannabinoids.
On a clinical level, products with pure extracts of CBD and THC remain therapeutically beneficial. Despite conflicts in research, emerging studies and recent literature speak in favor of the entourage effect. However, companies that market the entourage effect without prior knowledge could mislead the customer into believing a half-researched truth.